Which racial background is noted to have a lower prevalence of systemic lupus erythematosus (SLE)?

Individuals of Mediterranean descent are noted to have a lower prevalence of systemic lupus erythematosus (SLE) compared to other racial and ethnic groups. Epidemiological studies suggest that SLE is more commonly diagnosed in certain populations, particularly in African Americans, Hispanics, and Asians, who generally show a higher incidence of the disease. In contrast, studies indicate that people of Mediterranean descent experience lower rates of SLE, which could be attributed to genetic, environmental, and lifestyle factors that influence the disease's expression.

Understanding the varying prevalence of SLE among different races is important for healthcare providers, as it can influence screening practices and awareness efforts tailored to specific populations that may be at enhanced risk for developing this autoimmune disorder.