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The patient who drinks one cup of wine nightly with dinner is least likely to become an alcoholic because their drinking pattern suggests moderate alcohol consumption rather than excessive use. The context provided indicates a controlled and potentially socially acceptable behavior. Moderate drinking, especially if it's a ritual that involves one drink with a meal, is generally not associated with developing alcohol dependence.
In contrast, a patient with a family history of alcoholism has a higher risk due to genetic and environmental factors that can influence alcohol use behaviors. The patient whose wife complains about his drinking may present signs of problematic alcohol consumption, as the concern from a spouse often indicates potential issues. Finally, a patient who feels they drink all the time may be experiencing signs of dependency or problematic usage, which further increases their risk of becoming an alcoholic. Thus, moderation in drinking, as shown by the patient who consumes one cup of wine nightly with dinner, is a protective factor against the development of alcohol-related issues.