Which condition is characterized by recurrent lesions and is typically more severe in immunocompromised patients?

Herpes zoster, commonly known as shingles, is characterized by recurrent, painful lesions that develop due to the reactivation of the varicella-zoster virus (the same virus that causes chickenpox). In individuals with compromised immune systems, such as those undergoing chemotherapy, living with HIV, or taking immunosuppressive medications, the severity and frequency of outbreaks can markedly increase. This is because a healthy immune system typically keeps the virus latent and under control. However, when immune function is impaired, the virus can reactivate more easily, leading to the development of more severe symptoms and an increased risk of complications.

In contrast, conditions such as eczema, psoriasis, and contact dermatitis are often linked to immune responses and may not demonstrate the same pattern of severe recurrence associated specifically with herpes zoster in immunocompromised individuals. These other skin conditions frequently relate more to environmental factors, genetic predispositions, or even irritant responses, rather than a latent viral infection that can become exacerbated in immunocompromised patients.