Which common sign might indicate an overdose of anticholinergic drugs?

The indication of dry mucous membranes is a well-recognized sign of an overdose of anticholinergic drugs. Anticholinergic agents work by blocking the action of acetylcholine, which results in decreased secretion of saliva, sweat, and other bodily fluids. This blockade can create a dry environment in the mucous membranes, leading to symptoms such as dry mouth and reduced secretions from other mucous surfaces.

In the context of anticholinergic toxicity, patients often present with a classic triad of symptoms: dry skin, dry mucous membranes, and a flushed appearance. These manifestations arise due to the inhibition of the parasympathetic nervous system, which typically promotes secretions and fluid balance in the body.

Other options, while potentially relevant in various contexts, do not align with the typical presentations associated with anticholinergic overdose. Bradycardia is more commonly seen with cholinergic effects rather than anticholinergic ones. Hypotension can be a consequence of various drug overdoses but is not a hallmark of anticholinergic toxicity. Severe abdominal cramping can occur due to other causes, such as gastrointestinal disturbances or other drug effects, but it is not a primary feature of anticholinergic overdose.