What is indicated by the presence of Heberden's nodes in a 65-year-old patient?

The presence of Heberden's nodes is strongly indicative of degenerative joint disease, commonly known as osteoarthritis. These nodes are bony swellings that occur at the distal interphalangeal joints of the fingers, which can be seen in older adults. They are typically associated with the wear and tear of the cartilage that occurs in osteoarthritis, leading to the formation of bone spurs or osteophytes.

In individuals aged 65 and older, the development of Heberden's nodes signifies that the joints have experienced degenerative changes over time, characteristic of osteoarthritis. This condition often presents with joint pain, stiffness, and decreased range of motion, further aligning with the symptoms associated with degenerative joint disease. The age of the patient also supports this diagnosis, as osteoarthritis is most prevalent in older populations due to cumulative joint stress and aging processes.

Other conditions like osteoporosis, rheumatoid arthritis, and Reiter's syndrome do not typically present with Heberden's nodes. Osteoporosis primarily affects bone density rather than causing visible joint changes. Rheumatoid arthritis, an autoimmune condition, is more associated with symmetrical joint involvement and can lead to different types of nodules. Reiter's syndrome, which involves arthritis triggered by infection, usually affects