What associated condition is often seen in males with Fragile X syndrome?

Fragile X syndrome is a genetic condition characterized by a range of developmental issues and intellectual disabilities often more pronounced in males due to its X-linked inheritance pattern. One of the most commonly associated conditions seen in males with Fragile X syndrome is Attention Deficit Hyperactivity Disorder (ADHD).

Males with Fragile X syndrome frequently exhibit behavioral symptoms resembling those found in ADHD, such as attention deficits, hyperactivity, and impulsivity. This overlap is notable and highlights the neurodevelopmental impact of the genetic mutation associated with Fragile X syndrome.

While Down syndrome, Turner syndrome, and Marfan syndrome may pertain to different genetic conditions and can present their own sets of features and comorbidities, they are not directly associated with Fragile X syndrome as ADHD is. Such distinctions are important in understanding the specific comorbidities that can occur with Fragile X and how they may influence management and treatment strategies for affected individuals.