Patients with Down syndrome are at higher risk for all of the following except?

Patients with Down syndrome, also known as Trisomy 21, are known to have several health-related concerns. Atlantoaxial instability refers to a condition that can occur with cervical spine differences that make individuals with Down syndrome more prone to spinal cord compression, especially during activities like sports. Congenital heart disease is much more prevalent among individuals with Down syndrome, with a significant percentage having some form of heart defect. Early onset Alzheimer’s disease is also a noted concern, as individuals with Down syndrome have a higher prevalence of developing dementia at a younger age compared to the general population.

Melanoma, on the other hand, is a type of skin cancer that is not specifically associated with Down syndrome. While individuals with Down syndrome may still develop skin cancers, they do not have an increased risk of melanoma compared to individuals without Down syndrome. This distinction makes melanoma the exception among the listed conditions, which are more closely linked to the genetic and physiological factors inherent to Down syndrome.