During a sports physical, if a 16-year-old girl exhibits a split S2 during inspiration, what should the mother be advised?

The presence of a split S2 during inspiration is a normal physiological finding, especially in adolescents. During inspiration, there is an increase in venous return to the right side of the heart due to the negative intrathoracic pressure, which causes the pulmonary valve to close slightly later than the aortic valve. This is a common occurrence and reflects normal cardiac physiology, particularly in younger individuals whose cardiovascular systems are still maturing.

In this context, there is no need for further evaluation or restriction from physical activity, making it unnecessary to refer to a cardiologist, conduct a stress EKG, or advise avoidance of strenuous activities. Educating the mother on this aspect of normal adolescent heart sounds helps assure her of her daughter's health while also reinforcing an understanding of the body's physiological responses during differing states such as inspiration.