Acanthosis nigricans is typically associated with which of the following conditions?

Acanthosis nigricans is a skin condition characterized by dark, velvety patches in body folds and creases. It is most commonly linked to insulin resistance and is therefore typically associated with conditions such as obesity and diabetes. When obesity is present, excess fat can lead to increased insulin levels and subsequent skin changes, making it a significant factor in the development of acanthosis nigricans.

While diabetes, particularly type 2 diabetes, is also closely associated with this skin condition, it is especially pertinent in the context of metabolic syndrome, where acanthosis nigricans can serve as a marker for insulin resistance.

Colon cancer and tinea versicolor, on the other hand, do not have a strong association with acanthosis nigricans. Colon cancer does not typically present with this skin manifestation, and tinea versicolor is a fungal infection that results in discolored patches on the skin but is not related to the development of acanthosis nigricans.

The correct response reflects the well-established connection of acanthosis nigricans with obesity and diabetes, highlighting its role as a clinical indicator of underlying metabolic disturbances.